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Ecklonia stolonifera Okamura Extract Suppresses Myocardial Infarction-Induced Left Ventricular Systolic Dysfunction by Inhibiting p300-HAT Activity.
Nutrients. 2022 Jan 28;14(3):580.
Katagiri T, Sunagawa Y, Maekawa T, Funamoto M, Shimizu S, Shimizu K, Katanasaka Y, Komiyama M, Hawke P, Hara H, Mori K, Hasegawa K, Morimoto T
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Ecklonia cava extracts decrease hypertension-related vascular calcification by modulating PGC-1α and SOD2.
Biomed Pharmacother. 2022 Sep;153:113283.
Byun KA, Oh S, Yang JY, Lee SY, Son KH, Byun K
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Pyrogallol-Phloroglucinol-6 6-Bieckol on Attenuates High-Fat Diet-Induced Hypertension by Modulating Endothelial-to-Mesenchymal Transition in the Aorta of Mice.
Oxid Med Cell Longev. 2021 Jan 26;2021:8869085.
Son M, Oh S, Jang JT, Son KH, Byun K
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Ecklonia cava Extract and Its Derivative Dieckol Promote Vasodilation by Modulating Calcium Signaling and PI3K/AKT/eNOS Pathway in In Vitro and In Vivo Models.
Biomedicines. 2021 Apr 19;9(4):438.
Lu YA, Je JG, Hwang J, Jeon YJ, Ryu B
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Attenuating Effects of Dieckol on Endothelial Cell Dysfunction via Modulation of Th17/Treg Balance in the Intestine and Aorta of Spontaneously Hypertensive Rats.
Antioxidants (Basel). 2021 Feb 16;10(2):298.
Oh S, Shim M, Son M, Jang JT, Son KH, Byun K
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Pyrogallol-Phloroglucinol-6,6-Bieckol from Ecklonia cava Attenuates Tubular Epithelial Cell (TCMK-1) Death in Hypoxia/Reoxygenation Injury.
Mar Drugs. 2019 Oct 24;17(11):602.
Son M, Oh S, Choi CH, Park KY, Son KH, Byun K
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Mar Drugs. 2019, 17(5), 272.
Pyrogallol-Phloroglucinol-6,6'-Bieckol from Ecklonia cava Improved Blood Circulation in Diet-Induced Obese and Diet-Induced Hypertension Mouse Models.
Son M, Oh S, Lee HS, Ryu B, Jiang Y, Jang JT, Jeon YJ, Byun K.
Mar Drugs. 2018, 16(11), 441.
Protective Effect of Pyrogallol-Phloroglucinol-6,6-Bieckol from Ecklonia cava on Monocyte-Associated Vascular Dysfunction.
Oh S, Son M, Lee HS, Kim HS, Jeon YJ, Byun K.
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J Med Food. 2017 20(10), 944-950.
Cardioprotective Effects of a Phlorotannin Extract Against Doxorubicin-Induced Cardiotoxicity in a Rat Model.
Ahn HS, Lee DH, Kim TJ, Shin HC, Jeon HK.
Prev Nutr Food Sci. 2014, 19(3), 170-177.
Effect of Baechu Kimchi Added Ecklonia cava Extracts on High Glucose-induced Oxidative Stress in Human Umbilical Vein Endothelial Cells.
Lee HA, Song YO, Jang MS, Han JS.
J Am Coll Cardiol. 2014, 63(12S), A873.
Cardioprotective effects of Eckonia cava polyphenol against doxorubicin-induced cardiotoxicity in an amimal rat model with the evidence of electron microscopic finding.
Ahn, HS, Jeon, HK, Kim GH, Chung, WB, Cho, JS, Kim MJ, Cho, EJ, Jung, HO, Youn, HJ.
Biomed Res Int. 2014, 2014, 121396.
Alga Ecklonia bicyclis, Tribulus terrestris, and glucosamine oligosaccharide improve erectile function, sexual quality of life, and ejaculation function in patients with moderate mild-moderate erectile dysfunction: a prospective, randomized, placebo-controlled, single-blinded study.
Sansalone S, Leonardi R, Antonini G, Vitarelli A, Vespasiani G, Basic D, Morgia G, Cimino S, Russo GI.
European J Heart Failure. 2013, 12(1), S101.
Cardioprotective effects of seapolynol (polyphenol purified from ecklonia cava) against adriamycin-induced cardiomyopathy in an animal rat model.
Jeon HK, Lee DH, Youn HJ, Shin HC.
BMC Surg. 2012, 12 (Suppl 1), S22.
Observational study: daily treatment with a new compound ""tradamixina"" plus serenoa repens for two months improved the lower urinary tract symptoms.
Iacono F, Prezioso D, Illiano E, Ruffo A, Romeo G, Amato B.
BMC Surg. 2012, 12 (Suppl 1), S23.
Sexual asthenia: Tradamixina versus Tadalafil 5 mg daily.
Iacono F, Prezioso D, Illiano E, Romeo G, Ruffo A, Amato B.
Asian Pac J Trop Med. 2012, 5(5), 374-379.
Insulinotrophic and hypolipidemic effects of Ecklonia cava in streptozotocin-induced diabetic mice.
Kim MJ, Kim HK.
J Cell Biochem. 2012, 113(9), 2877-2883.
Antithrombotic and profibrinolytic activities of eckol and dieckol.
Kim TH, Ku SK, Bae JS.
Food Chem Toxicol. 2012, 50(6), 2188-2195.
Vascular barrier protective effects of phlorotannins on HMGB1-mediated proinflammatory responses in vitro and in vivo.
Kim TH, Ku SK, Lee T, Bae JS.
Phytother Res. 2012, 27, 148-151.
Pancreatic Lipase Inhibitory Activity of Phlorotannins Isolated from Eisenia bicyclis.
Eom SH, Lee MS, Lee EW, Kim YM, Kim TH.
Phytother Res. 2012, 26(3), 363-368.
Effects of 12-week Oral Supplementation of Ecklonia cava Polyphenols on Anthropometric and Blood Lipid Parameters in Overweight Korean Individuals: A Double-blind Randomized Clinical Trial.
Shin HC, Kim SH, Park Y, Lee BH, Hwang HJ.
J Med Food. 2012, 15(11), 1038-1044.
Effects of Ecklonia cava Polyphenol in Individuals with Hypercholesterolemia: A Pilot Study.
Lee DH, Park MY, Shim BJ, Youn HJ, Hwang HJ, Shin HC, Jeon HK.
European Heart J. 2012, 33(Supl 1), 328.
Cardioprotective effects of seapolynol (polyphenol purified from ecklonia cava) against adriamycin-induced cardiomyopathy in an animal rat model.
Jeon HK, Lee DH, Shin HC, Youn HJ, Kim KT.
Nutr Res Pract. 2011, 5(2), 93-100.
Effect of phlorotannins isolated from Ecklonia cava on angiotensin I-converting enzyme (ACE) inhibitory activity.
Wijesinghe WA, Ko SC, Jeon YJ.
Toxicol In Vitro. 2010, 24(2), 375-381.
Protective effects of dieckol isolated from Ecklonia cava against high glucose-induced
oxidative stress in human umbilical vein endothelial cells.
Lee SH, Han JS, Heo SJ, Hwang JY, Jeon YJ.
J Sci Food Agric. 2010, 90(2), 349-356.
Protective effects of enzymatic digest from Ecklonia cava against high glucose-induced oxidative stress in human umbilical vein endothelial cells.
Lee SH, Heo SJ, Hwang JY, Han JS, Jeon YJ.
Food Chem Toxicol. 2010, 48(6), 1682-1687.
Ecklonia cava extracts inhibit lipopolysaccharide induced inflammatory responses in human endothelial cells
Kim TH, Bae JS.
Arch Pharm Res. 2008, 31(12), 1564-1571.
Anti-hyperlipidemic dffect of an edible brown algae, Ecklonia stolonifera, and its
constituents
on poloxamer 407-induced hyperlipidemic and cholesterol-fed rats.
Yoon NY, Kim HR, Chung HY, Choi JS.
Carbohydrate Polymers. 2006, 66(2), 184-191.
An anticoagulative polysaccharide from an enzymatic hydrolysate of Ecklonia cava.
Athukorala Y, Jung WK, Vasanthan T, Jeon YJ,
Kor J Pharmacogn. 2006, 37(3), 200-205.
Antihypertensive effect of Ecklonia cava extract.
Hong JH, Son BS, Kim BK, Chee HY, Song KS, LeeBH, Shin HC, Lee KB.
Fisheries Sci. 2006, 72(6), 1292–1299.
Angiotensin-converting enzyme I inhibitory activity of phlorotannins from Ecklonia stolonifera.
Jung HA, Hyun SK, Kim HR, Choi JS.
J Food Agri Environ. 2006, 4(3-4), 17-19.
Angiotensin I-converting enzyme inhibitory activities of beverages made from sea algae
and commercially available tea extracts .
Nagai T, Suzuki N, Nagashima T.
Arch Pharm Res. 2003, 26(4), 286-293.
Antioxidative properties of brown algae polyphenolics and their perspectives as
chemopreventive agents against vascular risk factors.
Kang K, Park YJ, Hwang HJ, Kim SH, Lee JG, Shin HC.
Chem Pharm Bull (Tokyo). 1990, 38(1), 133-135.
Anti-plasmin inhibitor. VI. Structure of phlorofucofuroeckol A, a novel phlorotannin with both
dibenzo-1,4-dioxin and dibenzofuran elements, from Ecklonia kurome OKAMURA.
Fukuyama Y, Kodama M, Miura I, Kinzyo Z, Mori H, Nakayama Y, Takahashi M.
Chem Pharm Bull (Tokyo). 1989, 37(9), 2438-2440.
Anti-plasmin inhibitor. V. Structures of novel dimeric eckols isolated from the brown alga
Ecklonia kurome OKAMURA.
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Agric Biol Chem. 1989, 53(11), 3025-3030.
An anti-plasmin inhibitor, Eckol, isolated from the brown algae Ecklonia kurome OKAMURA.
Nakayama Y, Takahashi M, Fukuyama Y. Kinzyo Z.
Chem Pharm Bull (Tokyo). 1989, 37(2), 349-353.
Structure of an anti-plasmin inhibitor, Eckol, isolated from the brown alga Ecklonia kurome
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Eckols, Novel Phlorotannins with a Dibenzo-p-Dioxin Skeleton Possessing Inhibitory Effects on a2-Mcroblobulin from the Brown Alga Ecklonia kurome Okamura.
Fukuyama Y, Miura I, Kinzyo Z, Mori H, Kido M, Nakayama Y, Takahashi M, Ochi M,